Dickey's lab commenced studying mucin secretion twenty years back and previously identified The main element genes and proteins involved, showing how synaptotagmin along with a SNARE sophisticated, just like that present in neurons, contribute to The important thing strategy of Ca2+-induced membrane fusion.

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Critical Take note: NIH will not independently confirm info submitted to the GTR; it relies on submitters to deliver info that is definitely precise and never deceptive.

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Most medicines for these disorders work to scale back inflammation or develop the airways to help persons breathe better, but mucus is among the most critical challenge. Our research has produced the initial drug that might halt the secretion of mucins in its sp9 gaming tracks."

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